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Article

Translating epigenetics into clinic: focus on lupus

2 Aug 2017

Abstract excerpt

Systemic lupus erythematosus (SLE) is a chronic relapsing-remitting autoimmune disease with highly heterogeneous phenotypes. Biomarkers with high sensitivity and specificity are useful for early diagnosis as well as monitoring disease activity and long-term complications. Epigenetics potentially provide novel biomarkers in autoimmune diseases. These may include DNA methylation changes in relevant lupus-prone...

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PMID: 28785369
DOI: 10.1186/s13148-017-0378-7

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