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Article

Genetics in inclusion body myositis.

Current opinion in rheumatology - 1 Nov 2017

Rothwell Simon, Lilleker James B, Lamb Janine A

Abstract excerpt

PURPOSE OF REVIEW: To review the advances in our understanding of the genetics of inclusion body myositis (IBM) in the past year. RECENT FINDINGS: One large genetic association study focusing on immune-related genes in IBM has refined the association within the human leukocyte antigen (HLA) region to HLA-DRB1 alleles, and identified certain amino acid positions in HLA-DRB1 that may explain this risk. A suggestive...

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Topics

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Share to VCP gene
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-DRB1 Chains

Share to Muscle Fibers, Skeletal

Share to Myositis, Inclusion Body

Share to Proteomics

Share to SQSTM1 gene

Source

Open in PubMed Open full text

Identifiers

PMID: 28777108
DOI: 10.1097/BOR.0000000000000431
PMCID: PMC5625970

Genes

CCR5
FYCO1
SQSTM1
VCP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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