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Article

Sporadic inclusion body myositis: the genetic contributions to the pathogenesis

1 Jan 2014

Abstract excerpt

Sporadic inclusion body myositis (sIBM) is the commonest idiopathic inflammatory muscle disease in people over 50 years old. It is characterized by slowly progressive muscle weakness and atrophy, with typical pathological changes of inflammation, degeneration and mitochondrial abnormality in affected muscle fibres. The cause(s) of sIBM are still unknown, but are considered complex, with the contribution of...

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PMID: 24948216
DOI: 10.1186/1750-1172-9-88

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