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Article

Genetics of inclusion-body myositis.

Muscle & nerve - 1 May 2007

Needham M, Mastaglia F L, Garlepp M J

Abstract excerpt

Sporadic inclusion-body myositis (sIBM) is the most common acquired muscle disease in Caucasians over the age of 50 years. Pathologically it is marked by inflammatory, degenerative, and mitochondrial changes that interact in a yet-unknown way to cause progressive muscle degeneration and weakness. The cause of the disease is unknown, but it is thought to involve a complex interplay between environmental factors,...

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Identifiers

PMID: 17366591
DOI: 10.1002/mus.20766

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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