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Article

GNAS mutations in primary mucinous and non-mucinous lung adenocarcinomas.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Dec 2017

Ritterhouse Lauren L, Vivero Marina, Mino-Kenudson Mari, Sholl Lynette M, Iafrate A John, Nardi Valentina, Dong Fei

Abstract excerpt

GNAS mutations have been described in mucinous and non-mucinous epithelial neoplasms of the appendix, pancreas, and colon, with hotspot GNAS mutations found in up to two-thirds of pancreatic intraductal papillary mucinous neoplasms. Additionally, many GNAS-mutated tumors have concurrent mutations in the Ras/Raf pathway. The clinicopathologic features of GNAS-mutated lung carcinomas, however, have not yet been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to GTP-Binding Protein alpha Subunits, Gs

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Source

Identifiers

PMID: 28776576
DOI: 10.1038/modpathol.2017.88

Genes

GNAS
BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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