Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Screening and purification of natural products from actinomycetes that affect the cell shape of fission yeast.

Journal of cell science - 15 Sept 2017

Lewis Richard A, Li Juanjuan, Allenby Nicholas E E, Errington Jeffery, Hayles Jacqueline, Nurse Paul

Abstract excerpt

This study was designed to identify bioactive compounds that alter the cellular shape of the fission yeast Schizosaccharomyces pombe by affecting functions involved in the cell cycle or cell morphogenesis. We used a multidrug-sensitive fission yeast strain, SAK950 to screen a library of 657 actinomycete bacteria and identified 242 strains that induced eight different major shape phenotypes in S. pombe These...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actinomyces
Share to Biological Products

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Shape

Share to Checkpoint Kinase 1

Share to Cycloheximide

Share to Drug Evaluation, Preclinical

Share to Fatty Acids, Unsaturated

Share to Spectrometry, Mass, Electrospray Ionization

Source

Open in PubMed Open full text

Identifiers

PMID: 28775153
DOI: 10.1242/jcs.194571
PMCID: PMC5612171

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Screening and purification of natural products from actinomycetes that affect the cell shape of fission yeast.PMID 28775153Read ↗

Phenotypic screening meets natural products in drug discovery.Semantic proximity Read ↗

Gamma-butyrolactones: Streptomyces signalling molecules regulating antibiotic production and differentiation.Semantic proximity Read ↗

Olikomycin A–A Novel Calcium‐Dependent Lipopeptide with Antibiotic Activity Against Multidrug‐Resistant BacteriaSemantic proximity Read ↗

Identification of small molecules inducing apoptosis by cell-based assay using fission yeast deletion mutants.Semantic proximity Read ↗

Chemical genomics approach to identify genes associated with sensitivity to rapamycin in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

Analysis of the biological activity of a novel 24-membered macrolide JBIR-19 in Saccharomyces cerevisiae by the morphological imaging program CalMorph.Semantic proximity Read ↗

Effects of the tumor inhibitory triterpenoid avicin G on cell integrity, cytokinesis, and protein ubiquitination in fission yeast.Semantic proximity Read ↗

Anticancer Activity in PlanctomycetesSemantic proximity Read ↗

Novel inhibitors of bacterial cytokinesis identified by a cell-based antibiotic screening assay.Semantic proximity Read ↗

Enhanced bafilomycin A1 production in Streptomyces Griseobrunneus via protoplast fusion combined with high-throughput screening.Semantic proximity Read ↗

Cyanobacterial Metabolite Calothrixins: Recent Advances in Synthesis and Biological EvaluationSemantic proximity Read ↗

A genome-wide screening of potential target genes to enhance the antifungal activity of micafungin in Schizosaccharomyces pombe.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.