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Olikomycin A–A Novel Calcium‐Dependent Lipopeptide with Antibiotic Activity Against Multidrug‐Resistant Bacteria

2 Dec 2024

Abstract excerpt

Research into new antibiotics is becoming increasingly important as antibiotic resistance increases worldwide. The genus Streptomyces in particular is able to produce a wide range of antimicrobial products due to the large number of biosynthetic gene clusters (BGCs) in its genome. However, not all BGCs are expressed under laboratory conditions. In this work, deletion of the gene wblA, encoding a global regulator...

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Bioactive Compounds and Antitumor Agents
Cancer therapeutics and mechanisms
Microbial Natural Products and Biosynthesis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39620272
DOI: 10.1002/chem.202403985

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