Gamma-butyrolactones: Streptomyces signalling molecules regulating antibiotic production and differentiation.

doi:10.1016/j.mib.2006.04.003

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Article

Gamma-butyrolactones: Streptomyces signalling molecules regulating antibiotic production and differentiation.

Current opinion in microbiology - 1 Jun 2006

Takano Eriko

Abstract excerpt

Small signalling molecules called gamma-butyrolactones are mainly produced by Streptomyces species in which they regulate antibiotic production and morphological differentiation. Their molecular mechanism of action has recently been unravelled in several streptomycetes, revealing a diverse and complex system. Gamma-butyrolactones and their receptors also occur in some other Actinobacteria, suggesting that this is...

Topics

4-Butyrolactone
Anti-Bacterial Agents
Gene Expression Regulation, Bacterial
Genetic Variation
Signal Transduction
Streptomyces

Source

Open in PubMed

Identifiers

PMID: 16675291
DOI: 10.1016/j.mib.2006.04.003

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