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Article

Analysis of the biological activity of a novel 24-membered macrolide JBIR-19 in Saccharomyces cerevisiae by the morphological imaging program CalMorph.

FEMS yeast research - 1 May 2012

Ohnuki Shinsuke, Kobayashi Tomohide, Ogawa Hayato, Kozone Ikuko, Ueda Jun-Ya, Takagi Motoki, Shin-Ya Kazuo, Hirata Dai, Nogami Satoru, Ohya Yoshikazu

Abstract excerpt

To investigate the biological activity of a novel 24-membered macrolide compound, JBIR-19, isolated from the culture broth of the entomopathogenic fungus Metarhizium sp. fE61, morphological changes in yeast cells were examined using the automated image-processing program CalMorph. Principal components analysis was used to elucidate dynamic changes in the phenotypes, revealing two independent effects of JBIR-19 in...

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PMID: 22129199
DOI: 10.1111/j.1567-1364.2011.00770.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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