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Article

Superoxide Dismutase 2 is dispensable for platelet function.

Thrombosis and haemostasis - 5 Oct 2017

Fidler Trevor P, Rowley Jesse W, Araujo Claudia, Boudreau Luc H, Marti Alex, Souvenir Rhonda, Dale Kali, Boilard Eric, Weyrich Andrew S, Abel E Dale

Abstract excerpt

Increased intracellular reactive oxygen species (ROS) promote platelet activation. The sources of platelet-derived ROS are diverse and whether or not mitochondrial derived ROS, modulates platelet function is incompletely understood. Studies of platelets from patients with sickle cell disease, and diabetes suggest a correlation between mitochondrial ROS and platelet dysfunction. Therefore, we generated mice with a...

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Identifiers

PMID: 28771279
DOI: 10.1160/TH17-03-0174
PMCID: PMC5894334

Genes

SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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