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Article

Loss of matrix metalloproteinase 2 in platelets reduces arterial thrombosis in vivo.

The Journal of experimental medicine - 26 Oct 2009

Momi Stefania, Falcinelli Emanuela, Giannini Silvia, Ruggeri Loredana, Cecchetti Luca, Corazzi Teresa, Libert Claude, Gresele Paolo

Abstract excerpt

Platelet activation at a site of vascular injury is essential for the arrest of bleeding; however, excessive platelet activation at a site of arterial damage can result in the unwarranted formation of arterial thrombi, precipitating acute myocardial infarction, or ischemic stroke. Activation of platelets beyond the purpose of hemostasis may occur when substances facilitating thrombus growth and stability...

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Source

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Identifiers

PMID: 19808257
DOI: 10.1084/jem.20090687
PMCID: PMC2768852

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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