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Prediction of Alzheimer’s Disease-Associated Genes by Integration of GWAS Summary Data and Expression Data

7 Jan 2019

Abstract excerpt

Alzheimer's disease (AD) is the most common cause of dementia. It is the fifth leading cause of death among elderly people. With high genetic heritability (79%), finding the disease's causal genes is a crucial step in finding a treatment for AD. Following the International Genomics of Alzheimer's Project (IGAP), many disease-associated genes have been identified; however, we do not have enough knowledge about how...

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PMID: 30666269
DOI: 10.3389/fgene.2018.00653

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