Article
Association of genetic variation in IKZF1, ARID5B, and CEBPE and surrogates for early-life infections with the risk of acute lymphoblastic leukemia in Hispanic children.
Cancer causes & control : CCC - 1 Apr 2015
Hsu Ling-I, Chokkalingam Anand P, Briggs Farren B S, Walsh Kyle, Crouse Vonda, Fu Cecilia, Metayer Catherine, Wiemels Joseph L, Barcellos Lisa F, Buffler Patricia A
Abstract excerpt
BACKGROUND: Genome-wide association studies focusing on European-ancestry populations have identified ALL risk loci on IKZF1, ARID5B, and CEBPE. To capture the impacts of these genes on ALL risk in the California Hispanic population, we comprehensively assessed the variation within the genes and further assessed the joint effects between the genetic variation and surrogates for early-life infections (the presence...
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