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Article

Molecular Analysis of Genes CEBPA, NPM1, IDH1, and RUNX1 Polymorphisms as Biomarker Potential in Leukemia Patients.

Molecular carcinogenesis - 1 Feb 2025

Bashir Kashif, Ghafar Sadia Abdul, Rehman Afifa Tur, Waris Tayyaba, Farooq Fatima, Alamin Amin A

Abstract excerpt

Leukemia is found in approximately 2.3 million people worldwide and causes many deaths all over the world. This research study was conducted to figure out the link of single nucleotide polymorphisms of genes CEBPA (rs34529039), NPM1 (rs753788683), IDH1 (of rs11554137) and RUNX1 (rs13051066) polymorphisms as biomarker potential in leukemia patients. A total of 600 subjects were included in the study which included...

Read the complete abstract on PubMed

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Topics

Humans
Nucleophosmin
Male
Female
Polymorphism, Single Nucleotide
Core Binding Factor Alpha 2 Subunit
CCAAT-Enhancer-Binding Proteins
Isocitrate Dehydrogenase
Nuclear Proteins
Middle Aged
Biomarkers, Tumor
Case-Control Studies
Adult
Leukemia
Genetic Predisposition to Disease
Aged
Young Adult
Genotype

Source

Identifiers

PMID: 39565200
DOI: 10.1002/mc.23846

Genes

NPM1
RUNX1
IDH1

Provenance

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