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Identification of purity and prognosis‐related gene signature by network analysis and survival analysis in brain lower grade glioma

31 Aug 2020

Abstract excerpt

Tumour microenvironment of brain lower grade glioma (LGG) consists of non-tumour cells including stromal cells and immune cells mainly. These non-tumour cells dilute the purity of LGG and play pivotal roles in tumour growth and development, thereby affecting patient prognosis. Tumour purity is also associated with molecular subtypes of LGG. In this study, we discovered the most relevant module to purity by...

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PMID: 32869484
DOI: 10.1111/jcmm.15805

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