TP53 Mutation and Its Prognostic Significance in Waldenstrom's Macroglobulinemia.

doi:10.1158/1078-0432.CCR-17-0007

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Article

TP53 Mutation and Its Prognostic Significance in Waldenstrom's Macroglobulinemia.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2017

Poulain Stéphanie, Roumier Christophe, Bertrand Elisabeth, Renneville Aline, Caillault-Venet Aurélie, Doye Emmanuelle, Geffroy Sandrine, Sebda Sheherazade, Nibourel Olivier, Nudel Morgane, Herbaux Charles, Renaud Loic, Tomowiak Cécile, Guidez Stéphanie, Tricot Sabine, Roche-Lestienne Catherine, Quesnel Bruno, Preudhomme Claude, Leleu Xavier

Abstract excerpt

Purpose:TP53 is a tumor-suppressor gene that functions as a regulator influencing cellular responses to DNA damage, and TP53 alterations are associated with pejorative outcome in most B-lymphoid disorders. Little is known regarding TP53 alteration in Waldenstrom's macroglobulinemia (WM).Experimental Design: Here, we have explored the incidence of TP53 alteration using Sanger sequencing and ultradeep-targeted...

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PMID: 28754818
DOI: 10.1158/1078-0432.CCR-17-0007

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CXCR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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