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Article

The Diagnostic, Prognostic, and Therapeutic Utility of Molecular Testing in a Patient with Waldenstrom's Macroglobulinemia.

International journal of molecular sciences - 22 Sept 2017

Chin Collin K, Leslie Connull, Grove Carolyn S, Van Vliet Chris, Cheah Chan Yoon

Abstract excerpt

The application of molecular genomics and our understanding of its clinical implications in the diagnosis, prognostication and treatment of lymphoproliferative disorders has rapidly evolved over the past few years. Of particular importance are indolent B-cell malignancies where tumour cell survival and proliferation are commonly driven by mutations involving the B-cell receptor and downstream signalling pathways....

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Identifiers

PMID: 28937595
DOI: 10.3390/ijms18102038
PMCID: PMC5666720

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