Article
Genetic variation in the interleukin-28B gene is associated with spontaneous clearance and progression of hepatitis C virus in Moroccan patients.
PloS one - 1 Jan 2013
Ezzikouri Sayeh, Alaoui Rhimou, Rebbani Khadija, Brahim Ikram, Fakhir Fatima-Zohra, Nadir Salwa, Diepolder Helmut, Khakoo Salim I, Thursz Mark, Benjelloun Soumaya
Abstract excerpt
BACKGROUND: Genetic variation in the IL28B gene has been strongly associated with treatment outcomes, spontaneous clearance and progression of the hepatitis C virus infection (HCV). The aim of the present study was to investigate the role of polymorphisms at this locus with progression and outcome of HCV infection in a Moroccan population. METHODS: We analyzed a cohort of 438 individuals among them 232 patients...
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