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Article

A Toll-like receptor 7 single nucleotide polymorphism protects from advanced inflammation and fibrosis in male patients with chronic HCV-infection.

Journal of hepatology - 1 Aug 2007

Schott Eckart, Witt Heiko, Neumann Konrad, Taube Stefan, Oh Djin-Ye, Schreier Eckart, Vierich Sandra, Puhl Gero, Bergk Alexandra, Halangk Juliane, Weich Viola, Wiedenmann Bertram, Berg Thomas

Abstract excerpt

BACKGROUND/AIMS: HCV-infection leads to development of liver fibrosis, causing morbidity and mortality. Multiple factors influence the progression of fibrosis, including genetic factors. Since HCV is an RNA virus, a role for TLR7 in the immune response against HCV is likely. No systematic analysi...

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Source

Identifiers

PMID: 17512627
DOI: 10.1016/j.jhep.2007.03.021

Genes

TLR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17512627-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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