Article
SYCP3 regulates strand invasion activities of RAD51 and DMC1.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Sept 2017
Kobayashi Wataru, Hosoya Noriko, Machida Shinichi, Miyagawa Kiyoshi, Kurumizaka Hitoshi
Abstract excerpt
The synaptonemal complex is a higher-ordered proteinaceous architecture formed between homologous chromosomes. SYCP3 is a major component of the lateral/axial elements in the synaptonemal complex and is essential for meiotic recombination. Previous genetic studies showed that SYCP3 functions in meiotic homologous recombination biased to interhomologous chromosomes, by regulating the strand invasion activities of...
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