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Article

Sycp2 is essential for synaptonemal complex assembly, early meiotic recombination and homologous pairing in zebrafish spermatocytes.

PLoS genetics - 1 Feb 2020

Takemoto Kazumasa, Imai Yukiko, Saito Kenji, Kawasaki Toshihiro, Carlton Peter M, Ishiguro Kei-Ichiro, Sakai Noriyoshi

Abstract excerpt

Meiotic recombination is essential for faithful segregation of homologous chromosomes during gametogenesis. The progression of recombination is associated with dynamic changes in meiotic chromatin structures. However, whether Sycp2, a key structural component of meiotic chromatin, is required for the initiation of meiotic recombination is still unclear in vertebrates. Here, we describe that Sycp2 is required for...

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Identifiers

PMID: 32092049
DOI: 10.1371/journal.pgen.1008640
PMCID: PMC7062287

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