Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Saccharomyces cerevisiae Red1 protein exhibits nonhomologous DNA end-joining activity and potentiates Hop1-promoted pairing of double-stranded DNA.

The Journal of biological chemistry - 18 Aug 2017

Kshirsagar Rucha, Ghodke Indrajeet, Muniyappa K

Abstract excerpt

Elucidation of the function of synaptonemal complex (SC) in Saccharomyces cerevisiae has mainly focused on in vivo analysis of recombination-defective meiotic mutants. Consequently, significant gaps remain in the mechanistic understanding of the activities of various SC proteins and the functional relationships among them. S. cerevisiae Hop1 and Red1 are essential structural components of the SC axial/lateral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Pairing
Share to Chromosome Pairing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Circular

Share to DNA End-Joining Repair

Share to Microscopy, Atomic Force

Share to Recombinational DNA Repair

Share to Surface Plasmon Resonance

Share to Synaptonemal Complex

Source

Open in PubMed Open full text

Identifiers

PMID: 28642366
DOI: 10.1074/jbc.M117.796425
PMCID: PMC5566537

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Saccharomyces cerevisiae Red1 protein exhibits nonhomologous DNA end-joining activity and potentiates Hop1-promoted pairing of double-stranded DNA.PMID 28642366Read ↗

Meiosis-specific yeast Hop1 protein promotes synapsis of double-stranded DNA helices via the formation of guanine quartets.Semantic proximity Read ↗

Synaptonemal complex formation and meiotic checkpoint signaling are linked to the lateral element protein Red1.Semantic proximity Read ↗

The Mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair.Semantic proximity Read ↗

Probing the Potential Role of Non-B DNA Structures at Yeast Meiosis-Specific DNA Double-Strand Breaks.Semantic proximity Read ↗

Three distinct modes of Mec1/ATR and Tel1/ATM activation illustrate differential checkpoint targeting during budding yeast early meiosis.Semantic proximity Read ↗

Meiotic segregation, synapsis, and recombination checkpoint functions require physical interaction between the chromosomal proteins Red1p and Hop1p.Semantic proximity Read ↗

The meiosis-specific Hop2 protein of S. cerevisiae ensures synapsis between homologous chromosomes.Semantic proximity Read ↗

Genetic requirements and meiotic function of phosphorylation of the yeast axial element protein Red1.Semantic proximity Read ↗

Central region component1, a novel synaptonemal complex component, is essential for meiotic recombination initiation in rice.Semantic proximity Read ↗

The yeast Red1 protein localizes to the cores of meiotic chromosomes.Semantic proximity Read ↗

Novel attributes of Hed1 affect dynamics and activity of the Rad51 presynaptic filament during meiotic recombination.Semantic proximity Read ↗

Conserved HORMA domain-containing protein Hop1 stabilizes interaction between proteins of meiotic DNA break hotspots and chromosome axis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.