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Article

Comparative Visualization of the RNA Suboptimal Conformational Ensemble In Vivo.

Biophysical journal - 25 Jul 2017

Woods Chanin T, Lackey Lela, Williams Benfeard, Dokholyan Nikolay V, Gotz David, Laederach Alain

Abstract excerpt

When a ribonucleic acid (RNA) molecule folds, it often does not adopt a single, well-defined conformation. The folding energy landscape of an RNA is highly dependent on its nucleotide sequence and molecular environment. Cellular molecules sometimes alter the energy landscape, thereby changing the ensemble of likely low-energy conformations. The effects of these energy landscape changes on the conformational...

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Identifiers

PMID: 28625696
DOI: 10.1016/j.bpj.2017.05.031
PMCID: PMC5529173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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