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Article

Mot1, Ino80C, and NC2 Function Coordinately to Regulate Pervasive Transcription in Yeast and Mammals.

Molecular cell - 17 Aug 2017

Xue Yong, Pradhan Suman K, Sun Fei, Chronis Constantinos, Tran Nancy, Su Trent, Van Christopher, Vashisht Ajay, Wohlschlegel James, Peterson Craig L, Timmers H T Marc, Kurdistani Siavash K, Carey Michael F

Abstract excerpt

Pervasive transcription initiates from cryptic promoters and is observed in eukaryotes ranging from yeast to mammals. The Set2-Rpd3 regulatory system prevents cryptic promoter function within expressed genes. However, conserved systems that control pervasive transcription within intergenic regions have not been well established. Here we show that Mot1, Ino80 chromatin remodeling complex (Ino80C), and NC2...

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Identifiers

PMID: 28735899
DOI: 10.1016/j.molcel.2017.06.029
PMCID: PMC5573681

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TBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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