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Article

CHD1 remodelers regulate nucleosome spacing in vitro and align nucleosomal arrays over gene coding regions in S. pombe.

The EMBO journal - 28 Nov 2012

Pointner Julia, Persson Jenna, Prasad Punit, Norman-Axelsson Ulrika, Strålfors Annelie, Khorosjutina Olga, Krietenstein Nils, Svensson J Peter, Ekwall Karl, Korber Philipp

Abstract excerpt

Nucleosome positioning governs access to eukaryotic genomes. Many genes show a stereotypic organisation at their 5'end: a nucleosome free region just upstream of the transcription start site (TSS) followed by a regular nucleosomal array over the coding region. The determinants for this pattern are unclear, but nucleosome remodelers are likely critical. Here we study the role of remodelers in global nucleosome...

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Identifiers

PMID: 23103765
DOI: 10.1038/emboj.2012.289
PMCID: PMC3512388

Genes

CHD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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