Article
In silico analysis of Single Nucleotide Polymorphisms (SNPs) in human BRAF gene.
Gene - 25 Oct 2012
Hussain Muhammad Ramzan Manwar, Shaik Noor Ahmad, Al-Aama Jumana Yousuf, Asfour Hani Z, Khan Fatima Subhani, Masoodi Tariq Ahmad, Khan Muhammad Akhtar, Shaik Nazia Sultana
Abstract excerpt
BRAF gene mutations are frequently seen in both inherited and somatic diseases. However, the harmful mutations for BRAF gene have not been predicted in silico. Owing to the importance of BRAF gene in cell division, differentiation and secretion processes, the functional analysis was carried out to explore the possible association between genetic mutations and phenotypic variations. Genomic analysis of BRAF was...
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