Article
Sema3F (Semaphorin 3F) Selectively Drives an Extraembryonic Proangiogenic Program.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2017
Regano Donatella, Visintin Alessia, Clapero Fabiana, Bussolino Federico, Valdembri Donatella, Maione Federica, Serini Guido, Giraudo Enrico
Abstract excerpt
OBJECTIVE: Molecular pathways governing blood vessel patterning are vital to vertebrate development. Because of their ability to counteract proangiogenic factors, antiangiogenic secreted Sema3 (class 3 semaphorins) control embryonic vascular morphogenesis. However, if and how Sema3 may play a role in the control of extraembryonic vascular development is presently unknown. APPROACH AND RESULTS: By characterizing...
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