Article
Notch signaling regulates remodeling and vessel diameter in the extraembryonic yolk sac.
BMC developmental biology - 25 Feb 2011
Copeland Jessica N, Feng Yi, Neradugomma Naveen K, Fields Patrick E, Vivian Jay L
Abstract excerpt
BACKGROUND: The signaling cascades that direct the morphological differentiation of the vascular system during early embryogenesis are not well defined. Several signaling pathways, including Notch and VEGF signaling, are critical for the formation of the vasculature in the mouse. To further understand the role of Notch signaling during endothelial differentiation and the genes regulated by this pathway, both...
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