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Article

Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins.

Science (New York, N.Y.) - 14 Jan 2005

Gu Chenghua, Yoshida Yutaka, Livet Jean, Reimert Dorothy V, Mann Fanny, Merte Janna, Henderson Christopher E, Jessell Thomas M, Kolodkin Alex L, Ginty David D

Abstract excerpt

The development of a patterned vasculature is essential for normal organogenesis. We found that signaling by semaphorin 3E (Sema3E) and its receptor plexin-D1 controls endothelial cell positioning and the patterning of the developing vasculature in the mouse. Sema3E is highly expressed in developing somites, where it acts as a repulsive cue for plexin-D1-expressing endothelial cells of adjacent intersomitic...

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Identifiers

PMID: 15550623
DOI: 10.1126/science.1105416

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins.PMID 15550623Read ↗

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