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Article

Class-3 semaphorins: Potent multifunctional modulators for angiogenesis-associated diseases

5 Feb 2021

Abstract excerpt

Semaphorins, the neuronal guidance cues, were shown to have broad influences on pathophysiological processes such as bone remodeling, immune responses, and angiogenesis. In particular, Class-3 Semaphorins (SEMA3) is considered a vital regulator involved in angiogenesis. Scientific evidence has pointed to the role of angiogenesis in many diseases, and numerous efforts have been made to explore the possibilities of...

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PMID: 33545660
DOI: 10.1016/j.biopha.2021.111329

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