Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function.

Nature - 24 Jul 2003

Serini Guido, Valdembri Donatella, Zanivan Sara, Morterra Giulia, Burkhardt Constanze, Caccavari Francesca, Zammataro Luca, Primo Luca, Tamagnone Luca, Logan Malcolm, Tessier-Lavigne Marc, Taniguchi Masahiko, Püschel Andreas W, Bussolino Federico

Abstract excerpt

The motility and morphogenesis of endothelial cells is controlled by spatio-temporally regulated activation of integrin adhesion receptors, and integrin activation is stimulated by major determinants of vascular remodelling. In order for endothelial cells to be responsive to changes in activator...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autocrine Communication
Share to Cell Adhesion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chick Embryo

Share to Endothelium, Vascular

Share to Extracellular Matrix

Share to Integrins

Share to Morphogenesis

Share to Neovascularization, Physiologic

Source

Identifiers

PMID: 12879061
DOI: 10.1038/nature01784

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12879061-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function.PMID 12879061Read ↗

Differential endothelial transcriptomics identifies semaphorin 3G as a vascular class 3 semaphorin.Semantic proximity Read ↗

Endothelial cells on the move: dynamics in vascular morphogenesis and diseaseSemantic proximity Read ↗

Class 3 semaphorins in cardiovascular development.Semantic proximity Read ↗

Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins.Semantic proximity Read ↗

The angiogenic response is dictated by beta3 integrin on bone marrow-derived cells.Semantic proximity Read ↗

EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation.Semantic proximity Read ↗

Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading.Semantic proximity Read ↗

The Integrin Co-activator Kindlin-3 Is Expressed and Functional in a Non-hematopoietic Cell, the Endothelial CellSemantic proximity Read ↗

Class-3 semaphorins: Potent multifunctional modulators for angiogenesis-associated diseasesSemantic proximity Read ↗

Endothelial cell motility, coordination and pattern formation during vasculogenesisSemantic proximity Read ↗

Integrins in Vascular DevelopmentSemantic proximity Read ↗

SEMA3G regulates BMP9 inhibition of VEGF-mediated migration and network formation in pulmonary endothelial cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.