Article
Differential endothelial transcriptomics identifies semaphorin 3G as a vascular class 3 semaphorin.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2011
Kutschera Simone, Weber Holger, Weick Anja, De Smet Frederik, Genove Guillem, Takemoto Minoru, Prahst Claudia, Riedel Maria, Mikelis Constantinos, Baulande Sylvain, Champseix Catherine, Kummerer Petra, Conseiller Emmanuel, Multon Marie-Christine, Heroult Melanie, Bicknell Roy, Carmeliet Peter, Betsholtz Christer, Augustin Hellmut G
Abstract excerpt
OBJECTIVE: To characterize the role of a vascular-expressed class 3 semaphorin (semaphorin 3G [Sema3G]). METHODS AND RESULTS: Semaphorins have been identified as axon guidance molecules. Yet, they have more recently also been characterized as attractive and repulsive regulators of angiogenesis. Through a transcriptomic screen, we identified Sema3G as a molecule of angiogenic endothelial cells. Sema3G-deficient...
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