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Article

Replication confirms the association of loci in FOXE1, PDE8B, CAPZB and PDE10A with thyroid traits: a Genetics of Diabetes Audit and Research Tayside study (GoDARTS).

Pharmacogenetics and genomics - 1 Oct 2017

Soto-Pedre Enrique, Siddiqui Moneeza K, Doney Alex S, Palmer Colin N A, Pearson Ewan R, Leese Graham P

Abstract excerpt

OBJECTIVE: Replication of associations in genome-wide association studies is desirable to ensure that such signals are potentially clinically meaningful. This study aimed to replicate associations of selected single-nucleotide polymorphisms (SNPs) with hypothyroidism and serum thyroid-stimulating hormone (TSH) using electronic medical records (EMRs). PATIENTS AND METHODS: A cross-sectional study was carried out...

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Source

Identifiers

PMID: 28727628
DOI: 10.1097/FPC.0000000000000299

Genes

CAPZB
FOXE1
ABO
IGFBP5
INSR
ITPK1
NFIA
PRDM11
PTPN22
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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