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Article

A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents.

PloS one - 1 Jan 2017

Nielsen Tenna Ruest Haarmark, Appel Emil Vincent Rosenbaum, Svendstrup Mathilde, Ohrt Johanne Dam, Dahl Maria, Fonvig Cilius Esmann, Hollensted Mette, Have Christian Theil, Kadarmideen Haja N, Pedersen Oluf, Hansen Torben, Holm Jens-Christian, Grarup Niels

Abstract excerpt

BACKGROUND: Hypothyroidism is associated with obesity, and thyroid hormones are involved in the regulation of body composition, including fat mass. Genome-wide association studies (GWAS) in adults have identified 19 and 6 loci associated with plasma concentrations of thyroid stimulating hormone (TSH) and free thyroxine (fT4), respectively. OBJECTIVE: This study aimed to identify and characterize genetic variants...

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Identifiers

PMID: 28333968
DOI: 10.1371/journal.pone.0174204
PMCID: PMC5363901

Genes

FOXE1
VEGFA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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