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Article

Role of long-chain acyl-CoAs in the regulation of mycolic acid biosynthesis in mycobacteria.

Open biology - 1 Jul 2017

Tsai Yi Ting, Salzman Valentina, Cabruja Matías, Gago Gabriela, Gramajo Hugo

Abstract excerpt

One of the dominant features of the biology of Mycobacterium tuberculosis, and other mycobacteria, is the mycobacterial cell envelope with its exceptional complex composition. Mycolic acids are major and very specific components of the cell envelope and play a key role in its architecture and impermeability. Biosynthesis of mycolic acid (MA) precursors requires two types of fatty acid synthases, FAS I and FAS II,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28724694
DOI: 10.1098/rsob.170087
PMCID: PMC5541348

Genes

FAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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