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Article

Oleoyl coenzyme A regulates interaction of transcriptional regulator RaaS (Rv1219c) with DNA in mycobacteria.

The Journal of biological chemistry - 5 Sept 2014

Turapov Obolbek, Waddell Simon J, Burke Bernard, Glenn Sarah, Sarybaeva Asel A, Tudo Griselda, Labesse Gilles, Young Danielle I, Young Michael, Andrew Peter W, Butcher Philip D, Cohen-Gonsaud Martin, Mukamolova Galina V

Abstract excerpt

We have recently shown that RaaS (regulator of antimicrobial-assisted survival), encoded by Rv1219c in Mycobacterium tuberculosis and by bcg_1279c in Mycobacterium bovis bacillus Calmette-Guérin, plays an important role in mycobacterial survival in prolonged stationary phase and during murine infection. Here, we demonstrate that long chain acyl-CoA derivatives (oleoyl-CoA and, to lesser extent, palmitoyl-CoA)...

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Identifiers

PMID: 25012658
DOI: 10.1074/jbc.M114.577338
PMCID: PMC4155686

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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