Article
Enhanced trimethylamine metabolism and gut dysbiosis in type 2 diabetes mellitus with microalbumin
20 Nov 2023
Abstract excerpt
Background: Abnormal gut microbiota and blood trimethylamine-N-oxide (TMAO) metabolome have been reported in patients with type 2 diabetes mellitus (T2DM) and advanced diabetic nephropathy. This study aimed to investigate the gut microbiota profiles and a group of targeted urine metabolic characteristics in T2DM patients with or without microalbuminuria, to determine the correlation between the gut microbiota...
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