Article
Mechanism for G2 phase-specific nuclear export of the kinetochore protein CENP-F.
Cell cycle (Georgetown, Tex.) - 3 Aug 2017
Loftus Kyle M, Cui Heying, Coutavas Elias, King David S, Ceravolo Amanda, Pereiras Dylan, Solmaz Sozanne R
Abstract excerpt
Centromere protein F (CENP-F) is a component of the kinetochore and a regulator of cell cycle progression. CENP-F recruits the dynein transport machinery and orchestrates several cell cycle-specific transport events, including transport of the nucleus, mitochondria and chromosomes. A key regulatory step for several of these functions is likely the G2 phase-specific export of CENP-F from the nucleus to the...
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