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Article

Loss of CENP-F Results in Dilated Cardiomyopathy with Severe Disruption of Cardiac Myocyte Architecture.

Scientific reports - 15 May 2018

Manalo Annabelle, Schroer Alison K, Fenix Aidan M, Shancer Zoe, Coogan John, Brolsma Tanner, Burnette Dylan T, Merryman W David, Bader David M

Abstract excerpt

Centromere-binding protein F (CENP-F) is a very large and complex protein with many and varied binding partners including components of the microtubule network. Numerous CENP-F functions impacting diverse cellular behaviors have been identified. Importantly, emerging data have shown that CENP-F loss- or gain-of-function has critical effects on human development and disease. Still, it must be noted that data at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29765066
DOI: 10.1038/s41598-018-25774-1
PMCID: PMC5953941

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