Interleukin-6 (IL-6) rs1800796 and cyclin dependent kinase inhibitor (CDKN2A/CDKN2B) rs2383207 are associated with ischemic stroke in indigenous West African Men.

doi:10.1016/j.jns.2017.05.046

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Interleukin-6 (IL-6) rs1800796 and cyclin dependent kinase inhibitor (CDKN2A/CDKN2B) rs2383207 are associated with ischemic stroke in indigenous West African Men.

Journal of the neurological sciences - 15 Aug 2017

Akinyemi Rufus, Arnett Donna K, Tiwari Hemant K, Ovbiagele Bruce, Sarfo Fred, Srinivasasainagendra Vinodh, Irvin Marguerite Ryan, Adeoye Abiodun, Perry Rodney T, Akpalu Albert, Jenkins Carolyn, Owolabi Lukman, Obiako Reginald, Wahab Kolawole, Sanya Emmanuel, Komolafe Morenikeji, Fawale Michael, Adebayo Philip, Osaigbovo Godwin, Sunmonu Taofiki, Olowoyo Paul, Chukwuonye Innocent, Obiabo Yahaya, Akpa Onoja, Melikam Sylvia, Saulson Raelle, Kalaria Raj, Ogunniyi Adesola, Owolabi Mayowa

Abstract excerpt

BACKGROUND: Inherited genetic variations offer a possible explanation for the observed peculiarities of stroke in sub - Saharan African populations. Interleukin-6 polymorphisms have been previously associated with ischemic stroke in some non-African populations. AIM: Herein we investigated, for the first time, the association of genetic polymorphisms of IL-6, CDKN2A- CDKN2B and other genes with ischemic stroke...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain Ischemia

Share to Cyclin-Dependent Kinase Inhibitor p15

Share to Cyclin-Dependent Kinase Inhibitor p16

Share to Cyclin-Dependent Kinase Inhibitor p18

Share to Interleukin-6

Share to Sex Factors

Share to Stroke

Source

Open in PubMed Open full text

Identifiers

PMID: 28716248
DOI: 10.1016/j.jns.2017.05.046
PMCID: PMC5546618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interleukin-6 (IL-6) rs1800796 and cyclin dependent kinase inhibitor (CDKN2A/CDKN2B) rs2383207 are associated with ischemic stroke in indigenous West African Men.PMID 28716248Read ↗

APOL1, CDKN2A/CDKN2B, and HDAC9 polymorphisms and small vessel ischemic stroke.Semantic proximity Read ↗

Novel functional insights into ischemic stroke biology provided by the first genome-wide association study of stroke in indigenous Africans.Semantic proximity Read ↗

IL-6R Protective Variant rs7529229 Reduces Interleukin-6 Signaling and Contributes To A Decreased Ischemic Stroke RiskSemantic proximity Read ↗

Association between interleukin-6 (G174C and C572G) promoter gene polymorphisms and risk of ischemic stroke in North Indian population: a case-control study.Semantic proximity Read ↗

Stroke genomics in people of African ancestry: charting new paths.Semantic proximity Read ↗

IL-6R protective variant rs7529229 reduces interleukin-6 signaling and contributes to decreased ischemic stroke riskSemantic proximity Read ↗

Interleukin-6 174G/C polymorphism and ischemic stroke: a systematic review.Semantic proximity Read ↗

Association of IL-6-174G > C and -572C > G polymorphisms with risk of young ischemic stroke patients.Semantic proximity Read ↗

Association between Interleukin-6 (G174C and G572C) promoter gene polymorphisms and risk of ischaemic stroke: A meta-analysisSemantic proximity Read ↗

The association of functional polymorphisms of IL-6 gene promoter with ischemic stroke: analysis in two Chinese populations.Semantic proximity Read ↗

Linkage and association between interleukin-6 gene polymorphisms and ischemic stroke: a family-based study in the northern Chinese Han population.Semantic proximity Read ↗

Genome-wide association study of ischemic stroke risk in Sickle Cell confirms <i>ADAMTS2, CDK18</i>, uncovers 12 novel lociSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.