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Article

IL-6R protective variant rs7529229 reduces interleukin-6 signaling and contributes to decreased ischemic stroke risk

2020-06-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Interleukin-6 (IL-6) signaling is associated with the increased risk of coronary artery disease (CAD) and ischemic stroke (IS). Growing evidence shows that the minor allele of <italic>IL-6R</italic> rs7529229 variant could significantly increase the soluble IL-6 receptor levels and reduce CAD risk. However, it is largely unknown about the role of rs7529229 in IS,...

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Literature Corpus work
3694e4f9-519d-541a-9d7b-3096531dea01
DOI
10.21203/rs.3.rs-37472/v1
Open publication

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IL-6R protective variant rs7529229 reduces interleukin-6 signaling and contributes to decreased ischemic stroke riskDOI 10.21203/rs.3.rs-37472/v1
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