Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contribution of Genetic Factors to Lower DHEAS in Patients with Rheumatoid Arthritis.

Cellular and molecular neurobiology - 1 Jan 2018

Vernerova Lucia, Mravcova Martina, Paulikova Lucia, Vlcek Miroslav, Marko Andrea, Meskova Milada, Penesova Adela, Rovensky Jozef, Wendl Juraj, Raslova Katarina, Vohnout Branislav, Jochmanova Ivana, Lazurova Ivica, Killinger Zdenko, Steiner Guenter, Smolen Josef, Imrich Richard

Abstract excerpt

OBJECTIVE: Lower production of adrenal androgens has been confirmed in females with rheumatoid arthritis (RA); however, the mechanisms of this finding are not completely understood. The aim of our study was to assess the contribution of genetic factors associated with variability of dehydroepiandrosterone sulfate (DHEAS) levels to lower DHEAS in female RA patients. METHODS: 448 RA and 648 healthy controls were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dehydroepiandrosterone Sulfate

Share to Gene Frequency

Share to HHEX gene

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 28712091
DOI: 10.1007/s10571-017-0522-0

Genes

ZKSCAN5
HHEX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Contribution of Genetic Factors to Lower DHEAS in Patients with Rheumatoid Arthritis.PMID 28712091Read ↗

Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.Semantic proximity Read ↗

Possible association of CYP17 gene polymorphisms with the onset of rheumatoid arthritis.Semantic proximity Read ↗

Oestrogen receptor polymorphisms in female patients with rheumatoid arthritis.Semantic proximity Read ↗

A haplotype in STAT4 gene associated with rheumatoid arthritis in Caucasians is not associated in the Han Chinese population, but with the presence of rheumatoid factor.Semantic proximity Read ↗

CYB5A polymorphism increases androgens and reduces risk of rheumatoid arthritis in women.Semantic proximity Read ↗

Purine biosynthetic pathway genes and methotrexate response in rheumatoid arthritis patients among north Indians.Semantic proximity Read ↗

Influence of male sex on disease phenotype in familial rheumatoid arthritis.Semantic proximity Read ↗

The chromosome 7q region association with rheumatoid arthritis in females in a British population is not replicated in a North American case-control series.Semantic proximity Read ↗

Clinical and genetic risk factors for aromatase inhibitor-associated arthralgia in breast cancer survivors.Semantic proximity Read ↗

SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.