Article
Clinical and genetic risk factors for aromatase inhibitor-associated arthralgia in breast cancer survivors.
Breast (Edinburgh, Scotland) - 1 Feb 2020
Romero Sally A D, Su H Irene, Satagopan Jaya, Li Q Susan, Seluzicki Christina M, Dries Annika, DeMichele Angela M, Mao Jun J
Abstract excerpt
BACKGROUND: Arthralgia is a common and debilitating toxicity of aromatase inhibitors (AI) that leads to premature drug discontinuation. We sought to evaluate the clinical and genetic risk factors associated with AI-associated arthralgia (AIAA). METHODS: We performed a cross-sectional study among postmenopausal women with stage 0-III breast cancer who were prescribed a third-generation AI for adjuvant therapy. The...
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