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Article

3'-Terminated Overhangs Regulate DNA Double-Strand Break Processing in Escherichia coli.

G3 (Bethesda, Md.) - 7 Sept 2017

Đermić Edyta, Zahradka Davor, Vujaklija Dušica, Ivanković Siniša, Đermić Damir

Abstract excerpt

Double-strand breaks (DSBs) are lethal DNA lesions, which are repaired by homologous recombination in Escherichia coli To study DSB processing in vivo, we induced DSBs into the E. coli chromosome by γ-irradiation and measured chromosomal degradation. We show that the DNA degradation is regulated by RecA protein concentration and its rate of association with single-stranded DNA (ssDNA). RecA decreased DNA...

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Share to DNA Breaks, Double-Stranded
Share to DNA-Directed DNA Polymerase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Escherichia coli Proteins

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Source

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Identifiers

PMID: 28710290
DOI: 10.1534/g3.117.043521
PMCID: PMC5592934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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