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Article

Stability of linear DNA in recA mutant Escherichia coli cells reflects ongoing chromosomal DNA degradation.

Journal of bacteriology - 1 Feb 1997

Kuzminov A, Stahl F W

Abstract excerpt

To study the fate of linear DNA in Escherichia coli cells, we linearized plasmid DNA at a specific site in vivo and monitored its behavior in recA mutant cells deficient in recombinational repair. Earlier, we had found that in wild-type (WT) cells linearized DNA is degraded to completion by RecBCD nuclease. We had also found that in WT cells chi sites on linear DNA inhibit RecBCD degradation by turning off its...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9006046
DOI: 10.1128/jb.179.3.880-888.1997
PMCID: PMC178773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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