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Alteration of -656(G/T) and -607(C/A) polymorphisms in interleukin-18 (IL-18) gene in house dust mite-sensitive allergic rhinitis patients in Thailand.

Genetics and molecular research : GMR - 6 Jul 2017

Tungtrongchitr A, Jumpasri J, Sookrung N, Visitsunthorn N, Tantilipikorn P, Piboonpocanan O, Indrawattana N, Tungtrongchitr R, Chaicumpa W

Abstract excerpt

Allergic rhinitis (AR) is an IgE-mediated inflammation of the nasal membranes, which is naturally triggered by aeroallergens. House dust mites (HDM) are the most common inhalant allergens. Interleukin-18 (IL-18) has been established as an essential cytokine that can activate the generation of IgE. This randomized controlled study aimed to identify the possible relationship of the genetic variations in the IL-18...

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PMID: 28692122
DOI: 10.4238/gmr16039641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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