Article
Protective role of IL-18 -137G/C polymorphism in a North Indian population with asthma: a pilot study.
Cytokine - 1 Jan 2013
Birbian Niti, Singh Jagtar, Jindal Surinder Kumar
Abstract excerpt
BACKGROUND: IL-18, a pleiotropic, pro-inflammatory cytokine that plays a major role in innate as well as acquired immunity, has been implicated in asthma etiology and this is the first study investigating the role of IL-18 -137G/C (rs 187238) promoter polymorphism in asthma pathogenesis in a North Indian population. METHODS: A pilot study was conducted with a total of 824 subjects, out of which 410 were asthma...
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