Article
Interleukin-18 -607C/A gene polymorphism in Egyptian asthmatic children.
Molecular diagnosis & therapy - 1 Aug 2014
Shaaban Hala Hamdi, Mohy Abeer Mohamed, Abdel-Razek Abdel-Rahman Ahmed, Wahab Amira Abdel
Abstract excerpt
BACKGROUND: Asthma is a multifactorial respiratory disease determined by interactions of multiple disease susceptibility genes and environmental factors. Interleukin (IL)-18 is an important cytokine for initiating and perpetuating the catabolic and inflammatory response in allergic asthma. A number of single nucleotide polymorphisms that influence IL-18 production are found in the gene promoter region....
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