Article
Promoter polymorphism of the IL-18 gene is associated with atopic asthma in Tunisian children.
International journal of immunogenetics - 1 Feb 2008
Lachheb J, Chelbi H, Ammar J, Hamzaoui K, Hamzaoui A
Abstract excerpt
Several lines of evidence point to a relevant role of IL-18 in the process of asthma. Some studies suggest that the polymorphism in the gene of IL-18 can be involved in many inflammatory and atopic diseases such as asthma. The aim of our study is to estimate the frequency of the IL-18-607 C/A (rs 1946518) promoter polymorphism in Tunisian children with asthma. We investigated whether the presence of this...
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