Article
Interleukin-18/-607 gene polymorphism in allergic rhinitis.
International journal of pediatric otorhinolaryngology - 1 Jun 2006
Lee Heung-Man, Park Sook Ah, Chung Seung-Won, Woo Jeong Soo, Chae Sung Won, Lee Sang Hag, Kang Hee Joon, Hwang Soon Jae
Abstract excerpt
OBJECTIVES: Allergic rhinitis is a chronic inflammatory disease with a genetic background, and IL-18 (formerly IFN-gamma-inducing factor) is a well-known pro-inflammatory cytokine. The aim of this study was to investigate whether the IL-18/-607 promoter polymorphisms were associated with allergic rhinitis in the Korean population. STUDY DESIGN: Prospective study. METHODS: Deoxyribonucleic acid was obtained from...
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